Hepatitis B

• Hepatitis B is a virus (HBV) that can cause inflammation of the liver.
• It is spread when blood, semen, or another bodily fluid from an infected person enters the body of someone who is not infected through percutaneous (e.g., needlestick) exposure, direct contact with mucous membranes, sexual contact, or nonintact skin (e.g., wounds, cuts, scratches).
• For some people, hepatitis B infection is a short-term illness; but for others, it can become a long-term chronic infection.
• Infants and children are more likely to develop chronic hepatitis B infection than adults.
• Chronic hepatitis B can lead to long-term, serious health conditions, such as cirrhosis (scarring) of the liver or liver cancer.
• The best way to prevent hepatitis B is to get vaccinated.

A safe effective vaccine is available to prevent hepatitis B infection and is part of the routine recommended vaccination schedule for all infants starting at birth, children and adolescents who have not already completed the HBV vaccination series, and certain adults with increased risk for hepatitis B or severe disease. See below for more information.

• Hepatitis B Vaccine: https://www.cdc.gov/vaccines/vpd/hepb/index.html

Hepatitis B vaccine can also decrease the risk of infection in people exposed to hepatitis B, for example after percutaneous exposure, sexual assault, or perinatal exposure (i.e., baby born to HBV-infected mother), and should be given as soon as possible after exposure. In some situations, hepatitis B immune globulin (HBIG) should be given in addition to vaccine for added protection.

Hepatitis B is reportable in Orange County within seven (7) calendar days of identification. To report a case, health care providers/facilities should call Communicable Disease Control at 714-834-8180, fax reports to 714-560-4050, or mail to P.O. Box 6128, Santa Ana, CA 92706-0128.

Healthcare Professionals

• CA Providers:  Are you testing your patients for hepatitis B
• CDC Hepatitis B - Clinical Overview of Hepatitis B
• CDC Guidance for Evaluating Health-Care Personnel for Hepatitis B (MMWR Recommendations and Reports 2013; 62(RR10);1-19
• OC Health Care Agency - Viral Hepatitis Annual Report - 2026
• Perinatal Transmission of Hepatitis B
• Responding to HBV Exposures in Health Care Settings

Resources

• CDPH Hepatitis B Information
• CDC Hepatitis B Fact Sheet - English
• CDC Hepatitis B Fact Sheet - Spanish

For more information, see the Centers for Disease Control (CDC) website https://www.cdc.gov/hepatitis/hbv/index.htm.

Last Updated: 6/23/2026