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Monkeypox Vaccine Availability by Group

Monkeypox vaccine (Jynneos) supply is still limited and only available to exposed and high-risk groups described below. 

Who is eligible for monkeypox vaccine (JYNNEOS)? Due to the limited supply of vaccine, we are making it available only to those who are at highest risk.  Two groups are currently being offered vaccine; Those with known exposures, and those at highest risk for getting monkeypox based on what we have seen with the current outbreak.

For people with known exposures:

Orange County Public Health staff reach out to each person with monkeypox to find out about close contacts who would benefit from vaccination. Public Health staff reach out to those who were exposed and offer vaccine as quickly as possible.

Those considered at highest risk are people who fit the following groups of individuals:

Gay, bisexual, and other men (including cisgender and transgender men) who have sex with men (MSM) or transgender people who meet at least one of the following criteria:

  • Have been diagnosed with a bacterial sexually transmitted disease (e.g., chlamydia, gonorrhea, syphilis) in the past 12 months, OR
  • Have engaged in chemsex or group sex with other men, OR
  • Have had sex recently with anonymous male partners, OR
  • Have attended sex-on-premises venues (e.g., saunas, bathhouses, sex clubs), OR
  • Have had skin-to-skin or intimate contact (e.g., kissing, hugging) with persons at a large venue or event in the past 14 days, OR
  • Currently on HIV pre-exposure prophylaxis (PrEP), OR
  • Immunocompromised

People of any gender or sexual orientation that meet at least one of the following criteria:

  • Have engaged in survival and/or transactional sex, OR
  • Live with HIV, especially those with uncontrolled or advanced HIV disease, OR
  • Have had skin-to-skin or intimate contact with someone with suspected or confirmed monkeypox, including those who have not yet been confirmed by Public Health.


How can I get vaccinated with the monkeypox vaccine (JYNNEOS)?

To get vaccinated you must attest that you meet any of the criteria above by going to where you can also book your appointment for vaccination. Booking an appointment is preferred to, just showing up, because of the vaccine supply.


When and where is Monkeypox vaccine (JYNNEOS) being offered by the County?  

OCHCA is providing 1st and 2nd doses of Jynneos vaccine (for Monkeypox) as follows:

Every Wednesday and Friday in September, as well as October 5th and 7th.
Time: 10.00 am – 7.00 pm
Venue: SSA Central Regional Office (2020 W. Walnut Street, Santa Ana 92703). 

Vaccination will be provided to those who have any appointment first but walk-ins will be taken care of so long as there is vaccine available that day.


Last Updated: 9/26/2022