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On Friday, November 26, 2021 the WHO designated the a new SARS-CoV-2 Omicron variant as a Variant of Concern. It was first detected in South Africa and cases have subsequently been identified in Botswana and among travelers in more than a dozen countries around the globe. No cases have yet been identified in the US. There remains very limited data on the risk associated with the variant, though there is some early evidence that it may be more transmissible than currently circulating variants of SARS-CoV-2.