Tecovirimat (TPOXX) is an antiviral medication that is available for use to treat monkeypox under an expanded access investigational new drug (EA-IND) protocol (sometimes called “compassionate use”). It is the first-line medication to treat monkeypox in adults and children weighing 13kg or more.
The CDC IRB serves as the central IRB for the tecovirimat protocol; they have determined that its use dose not constitute research involving human subjects as defined by 45 CFR 46.102. More info...
